That is a difficult question to answer accurately. Do you mean with Ahrefs, SEMrush, or in general? I’m assuming that you’re asking about Ahrefs.
I wouldn’t go over 40 (the lower end of the “difficult” zone), and even then I’d be careful and recheck. As so many others have said, use it to get keyword ideas, then either check those ideas manually or with SEMrush.
It also depends on the keyword in question. Sometimes you’re in luck and simply find accurate information right off the bat. You never know.