It's different for every site, also most sandboxes are just temporarily, once the 'Google Dance' is over your site will come back to the SERPs higher. There's no exact number anyone can give you, you'll have to experiment yourself.
I have a site pr3, 2 years old with over 1000 links so I presume this would be no problem. I also have some sites a couple of months old which I have been building about 100 links a week for. They are for an offline business so I don't want them banned or even sandboxed really but I would like to blast them as I think one blast would get me virtually to the top of my business niche.
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