Mass e-Mail Tools

Hello, I'm building a list of emails and mobile numbers. I think I've got what I need to send the SMS messages in bulk - I'm wondering if anyone has a system down pat for sending mass emails.

Basically I want to hit the inbox. I will be marketing anything like

auto loans
personal loans
diet pills

more....

if you are still in the process of spamming, then I say it would be hard for you but if you want to find out a good source, I may be able to tell you via PM. But if your list is good, use SES or other SMTP servers out there.