Yes in 2019 your able to build a large following in Twitter without any bots or "special" methods. Many newbies are unaware that businesses are able to dominate there niche just by building a list of Twitter followwers. It works just like your building an email list. Your list of tweets will not only attract buyers from your direct list of followers but through inderect followers through hashtags and re-tweets.
For this method to work you will have to pay attention right from the beginning when setting up your profile to attract those followers. Your bio is very important and many people kind of put anything in there sometimes or just a link. Share what your business is all about and what makes it unique to other businesses out there. This is where people will create a persona of your business and decide whether to follow you or not, not just from your tweets.
The pictures your able to set up for both your header and profile image are very important as well. This will add legitmacy and credibility to your business and attract followers. You might not want to put a logo for your business and instead put something more fun that tells your followers your not just interested in selling to them.
If you already have a business list email them and let them know you have a Twitter account and ask for there follow. If they have you as a contact in their email then most likely they will ad you on Twitter as well. Then start putting your Twitter email in every location you can think off to attract new followers to your account. Places like webpages, forums, emails, on your business cards, and more.
Also follow people within your niche on Twitter, especially the ones who have a huge following. By doing this not only will they have a chance to follow you back but also gives you a chance to learn what they are doing on Twitter in order to gain such a large following.
People you follow will gain interest to your site and naturally click on your links in Tweets and in your Bio just to see what you are all about.
Re Tweeting also helps gain followers. It expands your reach within twitter and helps other people to see your Twitter handle and page as well which would not normally be seen through just regular tweets.