I'm not a big fan of the disavow tool, but with this you can let google know of links you do not want to take into consideration. Although, the link will still be there, unless you contact the site owner to remove it, or it gets deleted other way. For this reason, it's best to own tier1 links in your backlink profile. This can be done either renting, buying, or creating tier1 links to your site, which you later have control of.