Even if I found Thesis or Genesis is the way to go for authority site, I think that CTR or HeatMap is easier in term of placing your ads without additional theme coding tweak as well as plugins.
As long as you have quality content and profile sites, there is no need to worry about MFA or not MFA theme. It's not the excuse to theme that you'll get banned. The thing is most low quality or crappy sites are using MFA themes and get banned. Yet, it's not MFA themes that lets them to be banned.
If you really want to have a professional authority site, Thesis or Genesis is the choice.
For smaller or simple niche sites, you could still use Thesis and Genesis Frameworks. But, if you want to be easier for ads placement and ads optimize themes without doing the hassle with plugins or tweaking the themes, HeatMap or CTR theme is also the good choice.
I find HeatMap is good and easy to add the ads. Furthermore, their Click Missile is making easier to place more ads position as well as Resonsive Ads for Mobile, Tablet and Desktop.