1. SKAGs - Single Keyword Ad Groups (if you don't know what is it, there are plenty guides on the internet)
2. Start with a higher bid, lose some money, give Google some profit, then compare your Ads to the competitors. Work on the quality score - your ad texts should match the needs of the visitors as much as it possible, your landing page should also be on point, better quality score = lower CPC.
3. Test, test, test - different KWs, ad texts, extensions, demography.
4. Time - give your campaigns at least 1-2 months to grow (however sometimes you can have profit after 10-14 days, depends what you promote).
In a nutshell.