Advice needed please [Niche&Domain related]

Zhoom

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Hey all,

So after doing a fair amount of keyword research I've discovered a niche I'll want to work on, this niche being in the health economy.

I'll be ranking for a 4 word main keyword, followed by 5 other keywords (I've currently got 111 4+ keywords lined up also).

I've researched my competition, they have hardly any SEO onsite, backlinks and relative content to the search terms I'll be ranking for as mines more targeted around the subject.

My questions;

Due to being in the health economy I have medical / md websites to compete against, although its only 4 out of 10. Is this doable? They are targeting the same subject but mine will be more indepth / specific.

I've looked into .xyz domains vs. others, most say that they can rank just as well if not better with exact matches. I have an exact match although I've made it Plural (Selling aspect & Due to taken domain of non-plural) and also had to add an ending (service,portal,help,cure,fix etc.) to the end.
Will this affect me in ranking or have any impact? (blablasfix.xyz)

Thank you, sorry for the wall of text.
 
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The popular medical sites, if they are the same as the ones I'm thinking about it will be hard competition, and the domain extension shouldn't have a negative affect, feel free to correct me if you think I'm wrong though, just my two cents. Goodluck on this buddy!
 
The popular medical sites, if they are the same as the ones I'm thinking about it will be hard competition, and the domain extension shouldn't have a negative affect, feel free to correct me if you think I'm wrong though, just my two cents. Goodluck on this buddy!

Good stuff, thanks :)

The 4 websites are .com's & a .gov

Ranks 3-5, no 2's.

Top/First website is 1 year old (2015), 6 are 1995-1998 but 3 are 2000, 2013 & 2014.
Concerns are webmd, medical encyclopedia & a rank 3 site same niche, keyword in url x 2, title & meta.

Only three sites have the keyword in their title but different
( soap water dishes spoon, is water dishes soap spoon )
 
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