What's the most effective F/UF pattern?

Should I follow x people on Monday, unfollow x people on Tuesday, refollow x people on Wednesday, unfollow x people on Thursday, etc? Or should I keep following until 1000 following and then turn on unfollowing until 100 following and then restart following back up to 1000?
Thanks

Why not just follow between x and xxx each day ? Make it random.

There are many ways to follow/unfollow. You could also follow/unfollow on the same day. But if you do that it is best to not follow and unfollow at the same time. Start e.g. with only following and later in the day you switch to only following. This way your number of followings will remain about the same each day.