What affiliate program should I select for my website?

I have a website that has got large number of categories (Yellow Pages/Business categories theme) and receives about 25000 page views daily from US audience. Currently, I am running Adsense only. I am looking at exploring affiliate programs as I have heard and analyzed that affiliate programs could possibly earn me much more than what Adsense currently earns.

There are 2 ways I could go about it. First is embedding different affiliate products specific to each category within the respective categories and second, having one or 2 common products sitewide that could work for all. Achieving first is a heck of a job while achieving second is easier.

I am considering ClickBank.

Is there any contextual affiliate program platform that would automatically display the relevant product based on the page theme. I know this is far-fetched, but there's no harm in asking

Any thoughts?
Thanks!

I don't think aff programs have that feature, you need to select three or four different offers and test them to see which converts best with your audience. Go with business loan etc offers, you can find them on CJ or linkshare.

are they high end visitors? if so you can promote t harve and other high ticket products from different popular marketing gurus.
if not you can find low cost products too. finding relevant products shouldn't be that hard if you know your visitors.

find several kind of niche related to your page and go affplus choose some offers with US geo .
contact AM for these offers and test which kind of covert best.
For business site, i think finance & gambling type maybe fine.