I've used both SenukeX and UD. Both are great as far as "ease of use" is concerned. I would go with UD over SenukeX due to the price, but I personally have made the decision to not use either one in favor of sick submitter. Comparing Sick, because it has the ability to drop links on many of the various platforms that UD uses (Jcow, Wikis, article sites), I've had better success rates. For example I imported about 19k wikis into UD and only got a successful post on about 2200, whereas I've yielded a much higher success rate with Sick and a custom template (over 5k live links for a single platform whereas the 19k I put into UD was for 3 different platforms - moinmoin, wika, and mediawiki).
UD is my choice for ease of use, but Sick crushes it with regard to success rate on various platforms and with regard to the number of various platforms available to drop a link on (but UD is continually adding new platforms). I will note that Sick is not the most user friendly tool, but it sure is powerful if you have many of the custom templates.
I seem to remember that you are a Sick user, so as another fellow Sick user, I'd say you may not be happy with your results, but UD has a 30 day money back guarantee so you can try it out.