Thunderbird SMTP errors

I decided to give autoresponders a try again and figured since I've had luck with Thunderbird a couple years ago I'd try again but when I opened it up this morning, I had 260 emails in my inbox. My autoreply started up but after about 25 or 30 sent out, I get some kind of SMTP error. Now I've got over 200 emails sitting here that I can either dump or reply manually which I'm not going to do.

Anyone know why this SMTP error keeps happening?

Try to use the right smtp port for outgoing emails, its a usual problem for me too.

loverichie said:

Try to use the right smtp port for outgoing emails, its a usual problem for me too.

Click to expand...

I'm not sure what you mean. How would I change that?
Here is the error I get:

An (SMTP) error occurred while sending mail. The server responded: 4.7.0 Temporary System Problem. Try again later (WS). d19sm66615805ibh.8.