Skillshare or Domestika sponsoring ?

Hello,

i have a YouTube channel with around 100k subscribers. I have got some sponsor offerings including Domestika. My question now is, is it better to get sponsored by Skillshare or Domestika ? And is it possible
to sponsor two companys who are competitors like Domestika and Skillshare ? If i would sponsor Domestika, would I lose my ability to sponsor Skillshare maybe later when my channel gets bigger ?

Thanks for any reply

think 1st about your audience.. what is the best for them?, then who pays more and in what conditions (exclusivity has a price).