DNS uses port 43, its possible something on your machine is blocking it. The good news is it works fine for literally tens of thousands of people, so its something to your setup.
Please whitelist scrapebox and the entire scrapebox folder in all security software such as anti-virus, malware checkers and firewalls. Also you can whitelist in your router if your router supports it. Further you can try disabling real time scanning in your security software.
Take note that disabling security software (such as anti-virus, malware checkers and firewalls) often only stops new rules form forming, but allows existing rules to still fire. So you have to fully whitelist in the security software or uninstall the security software(as a test).
Further some security softwar requires you to whitelist in more then one place before it takes effect.
Also note that disabling a router firewall, does actually fully disable it.
I did just test it with
http://cars.com
http://dkdkdkdkdkdlllll.com
and it works fine for me showing cars.com taken and the other nonsense one available.
