I'm going to talk about my experience. I'm running a twitter account automatized with ifttt. I post some relevant pics using the rss to pic twit receipt and adding my affiliate link as caption, and also the every day at xx o'clock post a picture twit. The one adult related is working fine, the interactions are high, several favorites, several retwit and gaining followers every day.
I opened another not adult related and is not working so well. I think, that choosing the right niche is the clue, and for not adult niche, you need a lot of manual initial work because out of adult issues (maybe memes and fun pics would also work in auto mode) people run away from bots and only subscribe to accounts than interact (I think it is the reason that twitter is called a social network and not a news board)