Would you rather opt for fewer followers in twitter, but based on keywords for your site. Or more followers that could be about anything?
Well targeted followers is always a good thing, but the two don't have to be mutually exclusive... Find some twitterers in your niche with a lot of followers and follow the people who are following them. In that way you can get many followers who are also interested in your niche.
For example if I was Crashed, and I had a football (soccer) blog, I'd follow the followers of famous footballers (Messi, rooney, ronaldo, etc), specific teams (man u, chelsea, barca etc), football magazines and websites (soccernet, 101gg, etc). You should be able to find plenty.
If you have a niche where you can't find many twitterers, you can also follow people via a search term. E.G "come on united", "going out for some football", "need to get better at football",.... you get the picture
