I?m actually not sure if it?s possible to make money without bots. I?m being slightly facetious, but anyone who?s ever gotten rich online did it using bots. That includes folks like Mr Zuckerberg.
As far as making money with social networking sites, it depends on what you?re trying to do. Most of the well known social sites have pretty good spam filters, and too much competition trying to get past them. A technique that still works fairly well on any site is just adding followers in small amounts, and unfollowing anyone who doesn?t follow you back. For any given site, it?s a slow process, but distributed across many sites, you can reach a ton of people pretty quickly.
Once you have a big enough following, write good content and sell your affiliate products. If you?re not spammy about it, your accounts won?t get deleted, and you?ll have a decent cash cow.
Another way to make money is to find social sites that don?t have decent bots made for them and make decent bots for them. From there, put up a sales thread and sell to your blackhatworld friends. You can take it even further by setting up an affiliate program and letting others sell your product for you as well.
if you can find a method to make money without a bot doing it, then a bot will almost always help you make even more money.
So in short, yes, you can still make money with bots, and it?s probably still the easiest way to make any actual money online.