Many people have been wondering how to get a high CTR on adsense with niche sites. So here are a few tips to keep in mind: Blend your ads with the theme color. If you sites theme is red, then make your adsense ads red. Use Premium Ad Placement - If you don't know what this is then search something like "ad placement heat map" on Google When you're doing your keyword research you need to pick high converting keywords that have a high amount of advertisers targeting those keywords. Actually look at some of your competitors sites and see what ads are showing up. If my keyword is "red apples" and the ads that show up are not about apples, then your CTR is not going to be that high. Write good content. If you have crappy content, especially in your first few sentences, then people will immediately leave your page. So always use good relevant content. Once you find a good keyword that converts - Dominate the Niche! Find out what long tail keywords your competitors are targeting and ranking for and outrank them. The fact is, if one keyword has a high CTR, then it's likely that other keywords within that niche also have a high CTR because the same laser targeted advertisers are hitting those keywords as well.