i say in theory, because it can be it won't work at all
with WideCap/FreeCap/SocksCap you can proxify programs one by one and Proxy Firewall will proxify your whole system
i don't have any of these programs installed on my PC atm, but i can remember it wasn't too hard to configure them (they're very user friendly), you'll need a working HTTP(S), SOCKSv4 or SOCKSv5 proxy then you need to select the path where the executable of the program (Hummingbird) is located in your system and roughly that's all
once you've installed the programs, i think you can figure it out by yourself and/or read their FAQ, but there's no guarantee it will work for sure!
edited: but before you do anything, if i were you i'd check if Hummingbird is still working or not, because it uses API and since 1th Sept (twitter is switching to OAuth), there are a fair number of twitter apps which have issues now