Usage of trademarks in keywords is allowed in Google Ads and usage of trademarks in keywords is also officially allowed in Google Ads. Usage of trademarks in the ad copy (headlines, descriptions) is officially not allowed.
Go ahead and use Binance, Coinbase, etc in keywords (campaign or ad group wise respectively, do not bungle : in order words don't use Binance AND Coinbase in the same campaign, ad group, as the case may be) : If there are any issues upon doing that, then those issues are NOT arising due to usage of Binance, Coinbase, etc as keywords : in such a case you will need to analyze what blunder you would have done