Its according what PPC company you use.
Adwords doesn't usually allow any affiliated links on landing pages using their PPC program. So you would have to send the traffic to a page without any affiliate links.
Clickbank can be a real conundrum anyway with choosing the correct product that people are interested in purchasing.
I've made tonnes of cash in the past with social game guides for facebook games like cityville, and had good success with facebook ppc. But even this has got difficult, mainly because people are becoming more internet savvy and know where to get info for free.
You may have more success at software products through clickbank, rather than those sometimes shitty ebook products.
Trial and error i'm afraid!