I am unable to say for sure to be totally honest as I have never actually tested it. However I would go against what everyone else has said and say yes it will have a negative impact.
The reason I say this we already know for a fact Google do not like this type of practise so much so that they will disapprove any ads in Google ads for Capitalisation spam. Which tells me they would also ignore your title suggestions if you have used this method, at best they will auto correct the title you have used when it comes to using your titles in SERPs, at worst they could assign some sort of auto penalty or just ignore your title suggestion altogether and use other content on the page to populate tile on SERP's.
Further to this, it is not good for your visitors and visitor experience is something they have really worked on in recent years to improve the quality of sites they are ranking highest. So in my opinion yes it will have a negative impact however I have no proof to back my case it is just an opinion at this stage.