Craigslist and Affiliation

I've about 5K new and fresh leads (Emails) that i collect by posting ad on craigslist. I got this list by posting ad on Jobs category.

Can you please give me any idea that where should i use this leads to make money??

You could send them work at home or MMO offers. However, you will need to be sure your emails hit the inbox instead of the spam box, especially since 5k is not a lot. In any case, don't expect a big return on 5k emails collected through CL ads.

Out of curiosity, did you have no monetization plan in place the entire time you were collecting the emails?

Enryu is right on the money.

I think you should have had everything set up on your autoresponder account prior to collecting those emails. You
should have created an array of informative articles with your affiliate links embedded, tease them and get their juices flowing before sending them to an offer
that converts which you have tested beforehand.

Right now, it's going to be quite a challenge to get people interested in work to pay for a "work at home" offer (as tempting as it might be).

If I was looking for a job, I would get red lights flowing all around my skull if someone asked me to invest money for a job I had yet to even check for its validity.

Did you target your Ads on specific niche? if so you have to find out what is your audience. and if you let us know we might offer more help and ideas on how to turn those prospects into buyers.