Adsense vs Adx : What's the difference?

AdX Targeted at larger publishers, media companies, and enterprises with significant traffic. And also got strict eligibility criteria, typically requiring high traffic volumes and premium content. Often, publishers need to work with a Google Certified Publishing Partner (GCPP) to gain access.
 
Which one is best and why ?
AdX has a larger pool of advertisers and typically pays more. So it's better than Adsense.

Also, it's only available to publishers with certain number of visitors (usually in the millions) but with Google Ads partners like Ezoic and the rest you may get access to the program even when you have smaller number of visitors than is required. But you should know, your cut(pay) gets slightly lesser when you join through a partner (like Ezoic) than when you gain a direct access.
 
Adx is for big publishers, works on cpm model and needs high traffic. Adsense is for small web owners and works on cpc model.
 
Google AdSense and Google AdX (Ad Exchange) are both advertising platforms offered by Google, but they have some key differences:

Google AdSense:

AdSense is a program that allows website owners to display Google ads on their site and earn money when visitors click on or view the ads.
AdSense is more user-friendly and accessible to smaller publishers, bloggers, and website owners. It is easier to set up and manage, and it is open to a wider range of publishers.
AdSense offers contextual advertising, where ads are targeted based on the content of the website.
AdSense is a good starting point for those new to online advertising and looking to monetize their websites.
Google AdX (Ad Exchange):

AdX is a premium programmatic advertising marketplace where publishers can sell their ad inventory to advertisers in real-time auctions.
AdX is more geared towards larger publishers, ad networks, and agencies who have high traffic volumes and are looking for more advanced ad monetization solutions.
AdX offers more sophisticated ad targeting options and allows for greater control over ad placements, pricing, and ad formats.
AdX typically offers higher CPMs (cost per thousand impressions) compared to AdSense, but it also requires more technical expertise to set up and manage.
In summary, AdSense is a simpler and more accessible platform for smaller publishers looking to display Google ads on their websites, while AdX is a premium programmatic ad exchange for larger publishers and advertisers looking for more advanced ad monetization options and greater control over their ad inventory.
 
Google AdSense
Targets Small to Medium Publishers

while,

Google Ad Exchange (AdX)
Targets Large Publishers & Media Companies
 
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