The key is always TARGETED followers or replying TARGETED users.
I got tired of receiving thousands of clicks and failing to get a offer submit or even to actually sell the product.
Either way, building followers to your accounts is way better. I am currently targeting a TV show in one of my accounts (now 4 days old) and I'm bringing relevant content related to the show (spoilers, pics, etc.) and not trying to sell them anything. I have managed to gather 800 followers in 4 days (by doing following-if don't follow back-unfollow method via TweetAttacks), My account is relevant to them so they recommend to their friends and other people that like the show. I have gotten several @replies/@mentions asking for links to episodes, sales of the DVD and soundtrack, which means, I could make money off CPA (by referring them to episodes locked with gateways), sell them DVDs/Soundtrack via Amazon affiliate links and endless possibilities, and why would they want to do it with me? They trust me! I have provided relevant content to them and so they do not think I'm just trying to make money or scam the hell out of them.
You should also interact with them. Give shout outs to your 100th follower, 150th follower, reply back people who mention you, answer questions about the show (look on search if anyone is asking anything). Interaction also brings in followers.
Just my story, and it could be an inspiration. I am seeing stuff 4 days after I created my account but I'm still not sending links (cause it may keep future/possible followers away), so PATIENCE + TARGETED PEOPLE/FOLLOWERS/USERS is THE KEY!