Sure... Why not.
I opened a new a/c. Did NOTHING the same day when I opened this a/c. On 2nd day (of opening this new a/c) I went to Twellow and searched for my niche. Then I figured out WHO are the people having HUGE followings and write their "twitter usernames" in notepad (only top 10, geo targeted) Then opened "folllow" module of TA and started following. Settings were "50 to 150 A/cs" to follow in each session. Then waited for about 30 min (before starting new session). And the result? I am Today having 1500 followers with about 650 tweets.
Caution : You MUST not do "BULK UNFOLLOWING" in a single session. Just run small sessions (50-100 unfollowing each session) 2-3 times a day and set the gap like 5-15 seconds. Remember, Slow and steady wins the Race. So fly under the radar.
Hope it will help some of the new guys here