Yeah, yikes.. edible can be really intense anyway so having people with you helps to keep your mind in a good place. I've taken acid and mushrooms with gf before multiple times have have seen each other in states that you can't really see other people in too, and I've found those to be special experiences where you really get to see the inner workings of a person.. it can be about as close to spiritual as it gets really, and I've always found that really interesting
I've gone through depression and at that point consider ayahuasca too. In the end I got over it by travelling and most importantly I just shifted my focus to making money and drowned out everything else.. it can seem shallow at first to only care about money, but I tell you what it's the best cure for mental heatlh bs.. simplifies your priorities and life, and removes a lot of the focus on introspective shit, which was the cause of a lot of the crap I was unable to process.
I don't know if ayahuasca is a golden bullet for depression, but I found the idea interesting that when you do a ceremony you do multiple days back to back of taking it, and that with every one it gets stronger, and that you're confronted by your inner self during each one.. I felt like I needed my inner self to snap me out of my bs, ayahuasca seemed like the only direct way to do that.. in the end, it wasn't.