I would hand down keep Malwarebytes. SuperAntiSpyware Pro use to be top notch but they have failed me many times vs Malwarebytes. Super is coming out with version 5 very soon, maybe that will change things around for them.
When it comes to Antivirus and Spyware combo, you can't go wrong with NOD32. I use NOD32 and Malwarebytes and have kept clean. I would also install Comodo Free Firewall as well.
I have worked in the IT field for years and have been the one that gets out the spyware when others give up. I have more advanced techniques, but keep those updated and you should be fine.