What is something you think everyone should do at least once in their lives?

Learn Philosophy and science. That being said, "doing it once" in that case really is a lifelong study in the end.

Other than that.... play some single player game with incredible story, like SOMA, Hellblade, bioshock or Amnesia Rebirth.
 
Doing yoga just once in life : what benefit will that have ? Yoga done regularly on a consistent basis atleast for a few months only would have some benefits. Not, just doing yoga only once : instead of once, better do yoga consistently atleast for a few months.
 
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