I try to include my keyword up to three times in my add. In the title, body, and url. I also create a landing page on my website focused on that keyword where I include it in the page title, meta tags, url, and throughout the body usually in bold. This makes my page as relevant as possible to my ad and increases my quality score. Youll also increase your quality score by having a high ctr. I try maintaining 10%. To achieve that youll need a good ad copy and top 3 position or so. Usually after several days to a week of running your ads, google will start lowering your cpc. Being on pages 7-12 might bring in some clicks, but it probably wont be that significant enough to test a campaign and see if its profitable over the long run.