How long has the transfer been in effect? I had a similar situation with a .CA domain that does a lot of business in the US. We're still using the .CA, but we bought a similar .COM and did a redirect into the new .COM to kind of start fresh.
It took about 4-6 weeks, but after that the rankings started to shift to be more US based.
Also, do what beazt said and change this setting in Google Webmaster Tools, that should help out a bit.
Other than that, I'd also question what type of backlinks and such you already have. Are they from UK sites, or from US sites? That could also have an effect.