Second appeals rarely work if you just resubmit the same thing worded differently, that part is true. But I've seen accounts come back on the third or fourth try when people finally figured out the actual policy that got them flagged instead of the one they assumed.
The thing most people miss is that the suspension reason in the email is often vague on purpose. If it says "circumventing systems" or "suspicious payment activity" that's a different animal than a landing page or content issue, and the fix is totally different. Trying to appeal without knowing which bucket you're in is why so many get rejected repeatedly.
Couple things that have helped in cases I've seen: keep the appeal short and factual, don't argue or get emotional, and include verification docs proactively (business registration, ID, payment method proof) even if they didn't ask. Also if it's a Google Ads suspension specifically, sometimes getting a rep on chat/phone and having them note the account before you file gets a human looking at it instead of the automated pass.
If it's been rejected multiple times with nothing new added, honestly at some point the account is just gone and starting clean is faster than banging on a closed door. Knowing when to stop matters too.