Dont sell right away to the bunch. You need to groom them.
Start off by offering something free- grab some PLR stuff in different niches and set up a squeeze page and landing page for each and start offering it to the group.
Then you'll get a sub set of emails in each niche that would be a tighter target. Then you can slowly start to introduce appropriate targetted offers, whether its clickbank stuff or any other affiliate product you find.
Keep your tone conversational, treat them as if you are giving them a glimpse into your own life, and taking them along for the ride..
This way you build up loyalty, trust and can sell on a regular basis