My client list is over 400,000 and 2% or 8,000 normally will bounce. With each mailing I want to use a different from address to avoid the blocking delivery of 40% or more of my emails, but have the from address used in the mailing do a forward to the normal NoREply xxx net address, which is a never changing address. That way with the first use of the forwarding return address in the emails sent that address will not be blocked and my mail will be delivered. On the next mailing I'll use a different from address. Also the normal bounces that always occur (the 2% or 8,000) will be forwarded to i.e., NoREply xxx net and still be automatically processed by the sending software. This is what I'm needing and how do I do it?

you would need to configure your smtp server or you will need to filter your email database. Also, what software do you use to send the emails?